Effects of Beef Protein Consumption on Energy Intake

Maastricht University Medical Centre (MUMC)

Status: Completed

Conditions: Obesity; Severe Overweight

Treatments: Dietary Supplement: Differences in protein content (En%) of meals

Study type: Interventional

Funder types: Other

Identifiers

NCT01646749

NL41371

Details and patient eligibility

About

The purpose of this study is to determine ad libitum daily energy intake, body weight changes and appetite profile in response to protein/carbohydrate and fat ratio over 12 consecutive days, and in relation to age, gender, body mass index (BMI) and fat mass and obesity-associated (FTO) gene alleles.

Full description

The protein leverage hypothesis requires specific evidence whether energy intake would depend on a possible protein intake target in humans. Meat protein as complete protein may show most beneficial effects on variables regarding food intake regulation.

Enrollment: 30 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy
• Age 18-70 years
• BMI 18-35 kg/m2
• Non-smoking
• Weight stable

Exclusion criteria

• Smoking
• Use of medication
• More than moderate alcohol consumption
• Vegetarian

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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30 participants in 3 patient groups

Protein intake of 5 energy percent (En%)

Experimental group

Treatment:

Dietary Supplement: Differences in protein content (En%) of meals

Protein intake of 15 En%

Experimental group

Treatment:

Dietary Supplement: Differences in protein content (En%) of meals

Protein intake of 30 En%

Experimental group

Treatment:

Dietary Supplement: Differences in protein content (En%) of meals