Effects of Bilateral GPI DBS on Freezing of Gait in PD (PD GPI DBS)

Haiyan Zhou

Status: Completed

Conditions: Parkinson Disease

Study type: Observational

Funder types: Other

Identifiers

NCT03227250

GPIFOG

Details and patient eligibility

About

This study aims to evaluate the effect of deep brain stimulation in the the globus pallidus (Gpi) on freezing of gait in patients with Parkinson's disease.

Enrollment: 46 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria: (1) idiopathic PD, according to the MDS Parkinson's Disease Society Diagnostic Criteria17; (2) bilateral GPi-DBS implant according to a careful consideration of patients' symptom profiles (e.g., existence and severity of dyskinesia, dystonia, axial symptoms, or cognitive and mood problems); (3) onset of PD at or before 70 years of age; and (4) disease duration of more than 3 years at the time of surgery.

Patients were excluded if they had unstable vital signs or medical and psychiatric comorbidities at the time of the study.

Trial design

46 participants in 1 patient group

GPI DBS

Description:

patients who had freezing of gait and underwent deep brain stimulation (DBS) of the globus pallidus interna (GPi)