Effects of Black Tea on Type 2 Diabetes

National Nutrition and Food Technology Institute

Status: Completed

Conditions: Type 2 Diabetes Mellitus

Treatments: Dietary Supplement: Black Tea Extract

Study type: Interventional

Funder types: Other

Identifiers

NCT00916188

P/25/47/4564

Details and patient eligibility

About

The primary objective of this study is to evaluate the efficacy of different doses of black tea (150, 300, 450, 600 ml) in the test group compared to 150 ml in the control group, in improving oxidative stress, lipid profiles and insulin sensitivity.

Full description

A total of 45 patients of known T2DM (16 males and 29 females) were introduced into the controlled clinical trial and randomly assigned to either test (57.0 ± 7.9 yrs, n=23) or control (55.4 •± 8.3 yrs, n=22) group. Patients in control group were instructed to have only one cup (150 ml) of black tea/day, as a 2.5 g tea bag that had to be prepared in a standard way for one week (washout period). Patients in the test group were instructed to have 300, 450, and 600 ml (2, 3, and 4 cups, respectively) in weeks 2, 3 and 4 respectively. We assessed the change in serum glutathion, superoxidismutase, total antioxidant capacity, FBS, CRP, HbA1C, lipid profiles and fibrinogen during the end of each week.

Enrollment: 45 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of type 2 diabetes mellitus

Exclusion criteria

• Intake of antioxidant supplements during previous six months

Trial design

45 participants in 2 patient groups

Black Tea-Four Doses

Experimental group

Description:

One, 2, 3 and 4 cups (150 ml/cup) of Black tea/day for week 1, 2, 3, and 4, respectively.

Treatment:

Dietary Supplement: Black Tea Extract

Black Tea-One Dose

Active Comparator group

Description:

One cup (150 ml) of Black tea/day during study.

Treatment:

Dietary Supplement: Black Tea Extract