Effects of Bright-light Exposure Combined With Specific Exercise Training (BEST) Program in Patients With Cancer

Taipei Veterans General Hospital

Status: Enrolling

Conditions: Lung Neoplasm; Esophageal Neoplasms

Treatments: Behavioral: Daylight exposure combine walking; Behavioral: Stretching exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT05875870

2023-04-003B

Details and patient eligibility

About

This study plans to investigate the effectiveness of six-week light exposure combined with an exercise training program on improving sleep-wake rhythm, physical and mental symptoms, quality of life, one-year recurrence rate, and one-year survival rate of patients with lung and esophageal cancer.

Full description

This study plans to investigate the effectiveness of six-week light exposure combined with an exercise training program on improving sleep-wake rhythm, physical and mental symptoms, quality of life, one-year recurrence rate, and one-year survival rate of patients with lung and esophageal cancer.

Two groups, parallel, randomly assigned clinical trials, long-term follow-up, repeated measurement (pre-test, 6th week, 12th week, 6th month, 12th month, five times in total), and a design of single center recruitment. The experimental group receiving an intervention comprised six weeks of light exposure combined with exercise training. The active control group receiving six weeks of stretching exercise. With a double-blind study design of participant blind and outcomes assessor blind, subjects were recruited from the thoracic surgery clinic and thoracic surgery ward of a medical center in northern Taiwan.

Enrollment: 200 estimated patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients with newly diagnosed primary lung cancer or esophageal cancer, from the first stage to the third stage.
2. At least 20 years of age.
3. Able to communicate in Mandarin Chinese or Taiwanese.
4. Literate and free from cognitive disabilities.
5. The attending physician agrees to participate in the study.
6. Those who can connect to the Internet with mobile devices such as computers, mobile phones, and tablets, or those whose family members can assist in the operation.
7. Those with Karnofsky Performance Scale (KPS) greater than or equal to 70 points.
8. Those who are hospitalized for lung cancer or esophageal cancer lesion resection.

Exclusion criteria

1. Congestive heart failure.
2. Orthopedic diseases of the lower extremities that limit one's walking ability.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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200 participants in 2 patient groups

Experimental group

Experimental group

Description:

The rehabilitation program is composed of two parts: six-week bright-light exposure program and an exercise program.

Treatment:

Behavioral: Daylight exposure combine walking

Active control group

Active Comparator group

Description:

The active control group receives six weeks of a stretching exercise.

Treatment:

Behavioral: Stretching exercise