Effects of C-section Delivery on Infant Brain Development

Arkansas Children's Hospital Research Institute

Status: Terminated

Conditions: Healthy

Study type: Observational

Funder types: Other

Identifiers

NCT03277612

206515

Details and patient eligibility

About

The study will help investigators learn more about whether different delivery modes influence infant's brain development

Full description

For this study, the investigators are enrolling women who are pregnant with their second child who are planning to have a planned C-section or a spontaneous vaginal birth after C-section. The investigators will see the pregnant mom at 36 weeks pregnant and then have the mom and the baby return for a visit at 2 weeks postnatal.

Enrollment: 9 patients

Sex: Female

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Conceived without fertility treatments
• Singleton pregnancy recruited at or before 36 weeks of gestation
• Second parity with planned repeated C-section delivery or with planned spontaneous vaginal delivery after C-section.

Exclusion criteria

• Preexisting medical conditions
• Sexually transmitted diseases
• Medical complications developed during pregnancy
• Medical complications developed during labor and delivery
• Emergency c-section delivery
• Infants born preterm or post-term
• Infants needing mechanical ventilation, have congenital abnormalities, birth defects, intrauterine growth restriction, low Apgar score (<7), or other medical issues developed at birth or before 2 weeks of age affecting the outcome of interest as determined by the PI.

Trial design

9 participants in 2 patient groups

C-Section

Description:

Infants delivered by C-section

Vaginal Delivery

Description:

Infants delivered by spontaneous vaginal delivery after C-section.