Effects Of Caffeine On Cognitive Performance

University of Castilla-La Mancha

Status: Completed

Conditions: Caffeine

Treatments: Dietary Supplement: 3 mg/kg of caffeine; Dietary Supplement: PLACEBO; Dietary Supplement: 6 mg/kg of caffeine

Study type: Interventional

Funder types: Other

Identifiers

NCT05995314

CAF_MR_2023

Details and patient eligibility

About

Caffeine is a potent central nervous system stimulant that increases the activity in the prefrontal cortex and can improve cognitive skills. An improvement in these cognitive skills can lead to further benefits in athletic performance. Therefore, it is necessary to clarify the dose-response of caffeine on cognitive performance.The aim of this research will be to determine the effects of different doses of caffeine on sport-related cognitive aspects.

Full description

The investigators will require healthy, physically active young adults to complete three trials under the conditions: a) placebo, b) 3 mg/kg, or c) 6 mg/kg body mass of caffeine. In each trial, different cognitive abilities will be assessed using the following test batteries: reaction time (DynavisionTM D2), anticipation (Bassin Anticipation Timer), sustained attention (Go/No-Go and Eriksen Flanker Test) and memory tests. In addition, side effects and the perceived sensation index will be recorded 24 h after each test.

Enrollment: 30 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Physically active individuals ( >150 min/week moderate physical activity or >75 min/week vigorous physical activity)
• Individuals without serious and undiagnosed health problems.

Exclusion criteria

• Individuals with color blindness.
• Regular caffeine consumers (>3 cups of coffee/day).

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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30 participants in 3 patient groups, including a placebo group

PLACEBO

Placebo Comparator group

Description:

placebo (0 mg/kg of body mass of caffeine). The capsule will be filled with 3 mg/kg of body mass of cellulose.

Treatment:

Dietary Supplement: PLACEBO

3mg/kg

Experimental group

Description:

3 mg/kg of body mass of caffeine (99% caffeine, Bulkpowders, United Kingdom).

Treatment:

Dietary Supplement: 3 mg/kg of caffeine

6mg/kg

Experimental group

Description:

6 mg/kg of body mass of caffeine (99% caffeine, Bulkpowders, United Kingdom).

Treatment:

Dietary Supplement: 6 mg/kg of caffeine