Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels.

University of Saskatchewan

Status: Completed

Conditions: Asthma

Treatments: Other: caffeine; Other: No caffeine

Study type: Interventional

Funder types: Other

Identifiers

NCT01057875

BIO REB 09-186

Details and patient eligibility

About

To investigate whether or not the ingestion of caffeine with alter airway responsiveness to methacholine and/or change the level of exhaled nitric oxide.

Enrollment: 15 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• clinical diagnosis of asthma
• FEV1 greater than 65%

Exclusion criteria

• asthma is poorly controlled
• presence of other airway disease (e.g. COPD)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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15 participants in 2 patient groups, including a placebo group

coffee with caffeine

Experimental group

Treatment:

Other: caffeine

decaffeinated coffee

Placebo Comparator group

Description:

Starbuck's Grande Pike Roast Decaf

Treatment:

Other: No caffeine