Effects of Caffeine on Sleep-wake Regulation in Teenagers

Carolin Reichert

Status

Completed

Conditions

Caffeine

Adolescence

Treatments

Other: Caffeine

Other: Placebo

Study type

Interventional

Funder types

Other

Identifiers

2017-02118

Details and patient eligibility

About

The aim is to quantify the effects of one dose of caffeine (compared to placebo) on sleep and wakefulness in adolescents.

Enrollment

18 patients

Sex

Male

Ages

14 to 17 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Self-reported habitual caffeine consumption: min. 80 mg per month until max 300 mg per week as estimated from mean caffeine content per serving of caffeine containing beverages and food
Body-Mass-Index: 16.2-25.4
Informed Consent as documented by signature of participant
Informed Consent as documented by signature of legal representative

Exclusion criteria

Previous enrollment into the current study
Investigators' family members, employees or other dependent persons
Left-handedness
No normal current health as based on questionnaires, screenings of urine, and examination by the physician in charge
Drug use: Volunteers must be drug-free for the entire duration of the study, with no history of drug or alcohol dependency.
Participation in other clinical trials <3 months prior to study begin
Shift work <3 months prior to study begin
Transmeridian travel (>2 time zones) <1 month prior to study begin
Extreme Chronotype (Munich Chronotype Questionnaire [17], MCTQ <2 or >7)
Short or long sleep duration: subjective sleep duration during schooldays not between 6-10 h (based on MCTQ)
Inability to follow procedures
Insufficient knowledge of project language (German)
Circumstances endangering MRI safety
Non-compliance with sleep/wake times during ambulatory part (deviation of more than ±1.5 hour from scheduled times)