Effects of Cardiac Rehabilitation for Individuals With Transient Ischemic Attack

Toronto Rehabilitation Institute

Status: Completed

Conditions: Transient Ischemic Attack

Treatments: Behavioral: Cardiac Rehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT00929994

Brooks - 001

Details and patient eligibility

About

It is hypothesized that the addition of formal cardiac rehabilitation to standard care will result in long-term improvements in cardiovascular fitness and functional capacity in individuals who have suffered a transient ischemic attack (TIA) or minor stroke.

Furthermore, it is proposed that the addition of cardiac rehabilitation will influence depressive symptoms and cognition.

Full description

A transient ischemic attack (TIA) is defined as an episode of neurological dysfunction caused by focal brain ischemia lasting less than 24 hours. Once an individual has suffered a TIA, preventative measures can be taken to target modifiable risk factors, one of which is physical inactivity. The current proposal focuses on the use of an established model of care (cardiac rehabilitation (CR)) and applies it to those who have suffered a TIA in order to maximize physical activity and minimize risk of future cardiovascular events. This will be a one-group pre/post design study with a 3 month non-intervention period. Participants will undergo measures at baseline and 3 months (non intervention period) then after 6 months of cardiac rehabilitation (cardiovascular fitness, 6 minute walk test, cognition, and depressive symptoms).

Enrollment: 20 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with TIA
• Three months post-TIA
• Ability to understand the process and instructions for exercise training and provide informed consent

Exclusion criteria

• Resting Blood Pressure greater than 160/100 despite medication
• Other cardiovascular morbidity which would limit exercise tolerance (heart failure, abnormal BP responses or STsegment depression > 2 mm, symptomatic aortic stenosis, complex arrhythmias)
• Current and extensive exercise participation
• Hypertrophic Cardiomyopathy
• Unstable Angina
• Orthostatic BP decrease of > 20 mm Hg with symptoms
• Other musculoskeletal impairments which would limit the participants ability to walk sufficient durations
• Pain or other co-morbidities (e.g., unclipped aneurysms, uncontrolled seizures etc.) which would preclude participation
• Cognitive or behavioural issues that would limit participation in exercise testing and training

Trial design

20 participants in 1 patient group

Exercise

Description:

Following a 3 month non intervention period, participants will participate in Cardiac Rehabilitation, carrying out an exercise program which will last 6 months and combine both resistance and aerobic training.

Treatment:

Behavioral: Cardiac Rehabilitation