Effects of Cervical Lidocaine Spray on Pain Relief During Manual Vacuum Aspiration

UdonThani Hospital

Status: Active, not recruiting

Conditions: Obstetric Surgical Procedures; Lidocaine; Pain, Procedural

Treatments: Other: Placebo; Drug: 10 % lidocaine spray without adrenaline

Study type: Interventional

Funder types: Other

Identifiers

NCT06344637

2566/081 I

Details and patient eligibility

About

This randomized control trial aim to evaluate the effectiveness of local lidocaine spray application to the cervix on the reducing of pain score during the manual vacuum aspiration

Full description

This is a double blinded, placebo controlled study which compose of two arms. The treatment group is the local lidocaine spray application to the cervix with the intravenous opioid. The control group is the the intravenous opioid with the placebo (normal saline) before the manual vacuum aspiration. The outcome is to compare the visual analog pain score during and after procedure.

Enrollment: 216 patients

Sex: Female

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• female ageed 20 years to 60 years who have an indication for manual vacuum adpiration under intraveneous analgesia

Exclusion criteria

• patient with allergic to lidocaine or history of allergic to lidocaine
• patient with reproductive and urinary infection
• patient with abnormal vital sign
• patient with abnormal kidney and liver function test

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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216 participants in 2 patient groups, including a placebo group

10% lidocaine spray without adrenaline

Experimental group

Description:

4 puffs of 10% lidocaine spray without adrenaline apply on cervical os before manual vacuum aspiration

Treatment:

Drug: 10 % lidocaine spray without adrenaline

Placebo

Placebo Comparator group

Description:

4 puffs of normal saline apply on cervical os before manual vacuum aspiration

Treatment:

Other: Placebo