Effects of Cholecalciferol Supplementation on Bone Health and Muscle Strength in Adults During Post-burn Period

University of Liege

Status: Completed

Conditions: Vitamin D; Burn Injury

Treatments: Drug: Cholecalciferol

Study type: Interventional

Funder types: Other

Identifiers

NCT02092701

HDB1

Details and patient eligibility

About

Vitamin D has pleiotropic effects. Burn patients are at risk of hypovitaminosis D and may experience post-injury osteopenia and sarcopenia. Investigators hypothesized that vitamin D supplementation during one year can improve bone and muscle health in post-burn period.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• occurrence of injury between 2005 and 2011
• burn surface area (BSA) greater than 10%

Exclusion criteria

• Pregnancy, renal or liver failure, hypo or hyperparathyroidism, prior vitamin D substitution, treatment using systemic corticosteroids or antiepileptic drugs, regular exposure to ultraviolet B radiation (solarium), unstable cardiovascular disease or acute muscle or skeletal injury prohibiting physical exercise

Trial design

0 participants in 1 patient group

cholecalciferol

Experimental group

Treatment:

Drug: Cholecalciferol