ClinicalTrials.Veeva

Menu

Effects of Chronic Antihypertensive Therapy on Clinical Outcomes in Septic Shock

Rush logo

Rush

Status

Completed

Conditions

Atrial Fibrillation
Septic Shock

Study type

Observational

Funder types

Other

Identifiers

NCT02876341
16081002

Details and patient eligibility

About

Retrospective two-cohort study to determine the effect of chronic antihypertensive therapy on new onset atrial fibrillation and clinical outcomes in septic shock.

Full description

This will be a retrospective two-cohort study to determine the effect of chronic antihypertensive therapy on new onset atrial fibrillation and clinical outcomes in septic shock. The two cohorts will be septic shock patients that were: 1) not on either a chronic β-blocker or angiotensin-converting-enzyme inhibitor (ACE inhibitor) or 2) on a chronic β-blocker, on chronic ACE-Inhibitor, or on both chronic β-blocker and ACE-inhibitor

Enrollment

133 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult patients 18 years of age or older
  • Diagnosis of septic shock requiring vasopressor therapy (norepinephrine, epinephrine, phenylephrine, dopamine, or vasopressin)
  • Admitted to the medical intensive care unit (MICU) at Rush University Medical Center (RUMC)
  • Time frame: 01/01/2012 to 07/1/2016

Exclusion criteria

  • Pregnant patients
  • Transfer from outside hospital on vasopressors
  • Admitted to MICU in cardiopulmonary arrest
  • Prior arrest within 24 hours of admission to RUMC

Trial design

133 participants in 2 patient groups

No chronic antihypertensives
Description:
Not on either a chronic β-blocker or ACE-Inhibitor
Chronic antihypertensives
Description:
On a chronic β-blocker, on chronic ACE-Inhibitor, or on both chronic β-blocker and ACE-inhibitor

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems