Effects of Cocoa Flavanol on Skin Aging
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About
Photoaging is caused by the superposition of chronic ultraviolet (UV)-induced damage on the intrinsic aging process, and accounts for the majority of age-associated changes in skin appearance. Reactive oxygen species (ROS) likely contribute to this process. Strategies utilizing endogenous skin antioxidants as well as plant-derived or synthetic compounds have been examined.
Cocoa beans fresh from the tree are exceptionally rich in polyphenols, such as flavanol, and have a higher antioxidant capacity. The present study is designed to investigate the effects of long-term intake of a product rich in cocoa flavanols on facial wrinkles, hydration, elasticity and photosensitivity.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Healthy females aged ≥ 40 years
- Facial wrinkle grade ≥ 2
Exclusion criteria
- received medical or cosmetic treatment that interferes with the general aging process at least 3 months before the study
- reported taking functional foods 1 month before the study
- history of acute or chronic disease such as severe liver or kidney disease or uncontrolled diabetes
- history of allergies against any component of trial foods
- any visible skin disease that might be confused with a skin reaction to the test procedure
Trial design
Primary purpose
Allocation
Interventional model
Masking
64 participants in 2 patient groups, including a placebo group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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