Effects of Code Sepsis Implementation on Emergency Department (ED) Sepsis Care

Intermountain Health Care, Inc.

Status: Completed

Conditions: Sepsis

Treatments: Other: Code Sepsis protocol (full implementation)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04148989

K23GM129661 (U.S. NIH Grant/Contract)

1051053

Details and patient eligibility

About

Sepsis is a life-threatening complication of infection that can be difficult to recognize and treat promptly. Timely administration of antibiotics for emergency department (ED) patients with sepsis is challenging. The goal of this study is to determine the potential effectiveness and unintended consequences of reorganizing ED care for patients with suspected sepsis.

Enrollment: 180,402 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria (overall):

1. Adult (age ≥18 years)
2. ED patient at Intermountain Medical Center, Utah Valley Hospital, Dixie Regional Medical Center
3. Arrival to study emergency department (ED) during study period of 11/13/2018 to 2/12/2021.

Exclusion criteria (overall):

(1) Trauma patient

Trial design

Primary purpose: Health Services Research

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: Single Blind

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180,402 participants in 4 patient groups

Pre-implementation usual care (intervention site)

No Intervention group

Description:

Adult patients age ≥18 years who receive usual care after presenting to the ED of the intervention hospital emergency department before implementation of sepsis care reorganization (Code Sepsis implementation). The primary analysis will focus on the subset of patients with sepsis.

Code Sepsis post-implementation (intervention site)

Experimental group

Description:

Adult patients age ≥18 years presenting to the ED of the intervention hospital emergency department after implementation of sepsis care reorganization (Code Sepsis implementation). The primary analysis will focus on the subset of patients with sepsis.

Treatment:

Other: Code Sepsis protocol (full implementation)

Pre-implementation usual care (control sites)

No Intervention group

Description:

Adult patients age ≥18 years who receive usual care after presenting to the ED of the control hospital emergency department before implementation of sepsis care reorganization (Code Sepsis implementation) at the intervention hospital. The primary analysis will focus on the subset of patients with sepsis.

Post-implementation usual care (control sites)

No Intervention group

Description:

Adult patients age ≥18 years who receive usual care after presenting to the ED of the control hospital emergency department after implementation of sepsis care reorganization (Code Sepsis implementation) at the intervention hospital. The primary analysis will focus on the subset of patients with sepsis.