ClinicalTrials.Veeva

Menu

Effects of Cognitive Fatigue on Heart Rate Variability and Skin Conductance (FRESH)

N

Nanyang Technological University

Status

Enrolling

Conditions

Cognitive Fatigue
Mental Fatigue
Heart Rate Variability
Skin Conductance
Behavioral Performance

Treatments

Other: Baseline
Other: Fatigue Manipulation

Study type

Interventional

Funder types

Other

Identifiers

NCT05011318
COT-V4-2020-1-S002

Details and patient eligibility

About

This study aims to examine the effects of cognitive fatigue on heart rate variability and skin conductance and develop a machine learning model.

Full description

We hypothesize that increased cognitive fatigue would vary as a function of heart rate variability and skin conductance. A machine learning model will be developed that predicts cognitive fatigue through these physiological responses (Lee et al., 2021). Individual differences (i.e., age, gender, caffeine and food intake, body mass index, skin temperature, sleep quality, baseline physiology and behavioural performance) will be examined and accounted for.

Enrollment

162 estimated patients

Sex

All

Ages

18 to 35 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Singapore-based
  • Non-clinical
  • 18-35years

Exclusion criteria

  • Individuals with hearing difficulties or failing to meet the minimal threshold for normal hearing
  • Individuals with a history of ear, developmental, neurological, or psychiatric disorder

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

162 participants in 1 patient group

Fatigue Manipulation
Experimental group
Treatment:
Other: Fatigue Manipulation
Other: Baseline

Trial contacts and locations

1

Loading...

Central trial contact

Kar Fye Alvin Lee, PhD; GEORGIOS CHRISTOPOULOS, PhD

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems