Effects of Cognitive Intervention Therapy on Postoperative Delirium

Yonsei University

Status: Not yet enrolling

Conditions: Lung Neoplasms; Disc Herniation; Carcinoma, Hepatocellular; Spinal Stenosis

Treatments: Procedure: intervention group; Procedure: control group

Study type: Interventional

Funder types: Other

Identifiers

NCT06178939

4-2023-0872

Details and patient eligibility

About

This study is a prospective, single-center, randomized controlled trial to compare whether applying cognitive intervention therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium compared to conservative treatment.

Enrollment: 60 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Elderly patients aged 65 and above.
• Patients undergoing orthopedic, thoracic, or hepatopancreatobiliary surgery under general anesthesia with an expected surgery duration of 2 hours or more.
• Patients scheduled for arterial catheterization.

Exclusion criteria

• Patients with uncontrolled systemic conditions such as diabetes and hypertension.
• Those with visual impairment.
• Patients with cognitive impairment based on the MMSE-DS criteria.
• Individuals experiencing difficulty in communication.
• Those diagnosed with neurological disorders (such as brain hemorrhage, stroke, brain tumor, dementia, Parkinson's disease, cognitive impairment, depression, etc.).
• Patients diagnosed with alcohol or substance addiction.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

control group

Active Comparator group

Description:

The entire process is carried out according to Severance Hospital surgical protocols. The patients of control group will receive education from the research team about the importance of nutrition and exercise before and after surgery.

Treatment:

Procedure: control group

intervention group

Experimental group

Description:

For the intervention group, the entire process is carried out according to the Severance Hospital surgical protocol, and the research team provides education before surgery on the importance of nutrition and exercise before and after surgery. In addition, the cognitive training program developed by Rowan is taught with the goal of performing it for at least 10 hours before the surgery, it is conducted the training program after the surgery.

Treatment:

Procedure: intervention group