Effects of Cognitive-Oriented Intervention on Major Depressive Disorder

Mackay Medical College

Status: Completed

Conditions: Mental Health Issue

Treatments: Other: cognitive-oriented intervention program; Other: health education activities program

Study type: Interventional

Funder types: Other

Identifiers

NCT05296174

TSGH-IRB -1-102-05-019

Details and patient eligibility

About

The specific aims of the study were to explore the effects of the cognitive-oriented intervention program for promoting social support on perceived social supports, depression symptoms, and stress-coping strategies for patients with major depressive disorder in Taiwan.

Full description

Background: Based on the 2010 World Health Organization declaration, depression will be ranked second among the global disease burden by 2020, second only to cardiovascular disease. It has become a disease that incurs high personal and social costs, and thus warrants considerable concern regarding its mitigation and early prevention.

Purpose: The specific aims of the study were to explore the effects of the cognitive-oriented intervention program for promoting social support on perceived social supports, depression symptoms, and stress-coping strategies for patients with major depressive disorder in Taiwan.

Method: This study adopted a randomized controlled trial (RCT). Patients with major depressive disorder were recruited from acute psychiatric wards in a medical center in Northern Taiwan. The study was conducted from July 1, 2015, to December 31, 2016; 105 patients met the inclusion criteria, and 100 patients agreed to participate in the study and completed the evaluation. The participants were randomly assigned to intervention group or control group. The intervention group received a 40 mins social support intervention program once a week lasting for 6 weeks, and the control group received health education activities with the same frequency as the intervention group. All participants were assessed by questionnaires before and after the intervention. Statistical analyses were performed by using descriptive statistics, independent sample t tests, and linear multiple regression analysis.

Enrollment: 105 patients

Sex: All

Ages: 20+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• diagnosed with MDD by a psychiatrist
• over 20 years of age
• able to speak Mandarin or Taiwanese and able to write.

Exclusion criteria

• patients who were diagnosed with other psychiatric disorders
• with severe cognitive impairment or who could not make conversation acceptably were excluded.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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105 participants in 2 patient groups

cognitive-oriented intervention program

Experimental group

Description:

The intervention group received a 40 mins social support intervention program once a week lasting for 6 weeks. All participants were assessed by questionnaires before and after the intervention.

Treatment:

Other: cognitive-oriented intervention program

received health education program

Active Comparator group

Description:

The control group received health education activities with the same frequency as the intervention group. All participants were assessed by questionnaires before and after the intervention.

Treatment:

Other: health education activities program