Effects of Cognitive Strategy Training on Daily Function in People With Subjective Cognitive Decline

National Cheng Kung University

Status: Unknown

Conditions: Subjective Cognitive Decline

Treatments: Behavioral: Cognitive strategy training; Behavioral: group interactive game

Study type: Interventional

Funder types: Other

Identifiers

NCT04330404

NCKU HREC-E-108-388-2

Details and patient eligibility

About

Subjective cognitive decline (SCD) is the transitional state between normal aging and mild cognitive impairment. SCD is defined as having self-perceived declines in any cognitive domain over time; having normal performance on cognitive testing; no dementia or depression. Cognitive difficulties can lead to a decline on daily function and quality of life. Early intervention can prevent SCD from developing into dementia.

Cognitive strategy training (CST) aims to generate individualized strategies to solve cognitive problems, which can be effective to improve daily functions and performances. However, there is limited clinical research aimed at improving daily functions for SCD. Most non-pharmacological studies have conducted objective cognitive training, which may not enhance daily performance. Previous studies also seldom examine the effectiveness of the intervention to improve daily function, quality of life, self-efficacy and motivation.

This study adopts a quasi-experimental design. The investigators will recruit 80 community-dwelling people with SCD who are aged 55 and older. There will be 40 participants in each group. The experimental group will receive the CST. The active control group will receive group interactive game. Both groups will have 8 sessions for one hour per week for a total of 8 weeks. Outcome measures include daily function, self-efficacy, motivation for change, and quality of life. Assessments will be performed at baseline, post-intervention, and 3-month follow-up. The demographic data of the two groups will be compared using the independent sample t-test and chi-square test. Changes on outcomes between the two groups will be analyzed by two-way ANOVA. This study was approved by the Human Research Ethics Committee at National Cheng Kung University. All participants provided written informed consent before testing.

This study aims to (1) examine the feasibility of the CST in community-dwelling people with SCD; (2) explore the efficacy of the CST on daily function, self-efficacy, motivation for change, and quality of life.

Enrollment: 80 estimated patients

Sex: All

Ages: 55+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• aged 55 and above
• live in community
• self-perceived decline in cognition compared to five years ago
• subjective cognitive decline, Cognitive Failure Questionnaire (CFQ) score above zero.

Exclusion criteria

• objective cognitive impairment, Taiwanese version of the Montreal Cognitive Assessment (MoCA-T) scores below 24
• any medical, neurological or psychiatric disorders, Brief Symptom Rating Scale (BSRS-5) scores 10 or more
• severe visual, auditory, verbal or physical impairments interfere with communication, command compliance, and strategy execution
• participate in other research related to cognitive strategy at the same time.

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

Cognitive strategy training

Experimental group

Description:

The experimental group will receive the Cognitive strategy training (CST), which includes awareness enhancement, cognitive-related education, discussion of everyday cognitive difficulties, generation of cognitive strategies, cognitive strategy practice, and homework assignments.

Treatment:

Behavioral: Cognitive strategy training

group interactive game

Active Comparator group

Description:

The active control group will receive group interactive game, including table games and games using songs, balloons, newspapers and so on.

Treatment:

Behavioral: group interactive game