Effects of Cold Application and Heparinoid on Periorbital Edema and Ecchymosis

Necmettin Erbakan University

Status: Completed

Conditions: Ecchymosis; Neurological Disorder; Cryotherapy Effect; Periorbital Edema; Nursing Caries

Treatments: Drug: Heparinoids Topical Cream; Other: Cold gel pack; Other: Routine care

Study type: Interventional

Funder types: Other

Identifiers

NCT04119297

3791

Details and patient eligibility

About

During surgery, blood leaking from damaged blood vessels spread to the periorbital area may cause periorbital edema and ecchymosis after anterior craniotomy. This study was carried out to determine the effects of the cold application and the local heparinoid on periorbital edema and ecchymosis after craniotomy.

Full description

Periorbital edema and ecchymosis are common after anterior craniotomy. Periorbital edema and ecchymosis are not complications, they are natural outcomes of surgical trauma. However, periorbital edema prevents pupil examination and causes the patient to experience fear and anxiety with accompanying ecchymosis. Periorbital edema rate after anterior craniotomy was 36.8-100%, ecchymosis rate was 62.5%, and 30% of patients with edema did not have a pupil examination for the first 36 hours after craniotomy.The present study was carried out to determine the effects of the heparinoid creams and regular cold application performed using gel packs in controlling periorbital edema and ecchymosis after craniotomy.

Enrollment: 90 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria: The eligible participants were those

• who were aged 18 years and older
• who had Glasgow Coma Scale score > 15
• who had no mental and physical problems that interfere with communication
• whose vital signs were normal
• who had no ptosis
• who volunteered to participate and signed the informed consent form

Exclusion Criteria:The participants excluded from the study;

• who had Glasgow Coma Scale score < 15
• who died during surgery
• ptosis formed after surgery
• who refused to participate

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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90 participants in 3 patient groups

Control

Active Comparator group

Description:

Routine care (Irregular cold application or gauze bandages wetted with isotonic solution or once daily heparinoid cream application) of the clinic was applied.

Treatment:

Other: Routine care

Cold application

Experimental group

Description:

Cold application was applied for three days after craniotomy.

Treatment:

Other: Cold gel pack

Heparinoid group

Experimental group

Description:

Heparinoid cream was applied for three days after craniotomy

Treatment:

Drug: Heparinoids Topical Cream