Effects of Collagen Peptide Supplementation on Muscle and Tendon Damage and Function

Catholic University (KU) of Leuven

Status: Completed

Conditions: Healthy Male Subjects; Exercise

Treatments: Dietary Supplement: whey protein + collagen peptide; Dietary Supplement: whey protein

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT05425407

S64402

Details and patient eligibility

About

The aim of the study is to investigate the acute and short-term effects of collagen peptides (Collagen Peptan) on muscle and connective tissue during an eccentric overload training period. Currently, all studies investigating the effects of post-exercise collagen supplementation did this in the absence of whey proteins, which are part of the standard recommendations for post-exercise recovery. The investigators will therefore investigate whether the combined intake of whey proteins and collagen peptides ensures a better recovery of exercise performance and whether it can prevent or reduce symptoms of muscle and tendon overload during a three-week eccentric overload training period (n = 22).

Enrollment: 22 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sports participation, including general fitness training, between 2 and 5 hours max per week
• Body mass index between 18.5 and 25

Exclusion criteria

• Any kind of injury/pathology that is a contra-indication to perform high-intensity exercise - Intake of any medication or nutritional supplement that could impact muscle protein synthesis and/or exercise performance during the period of the study
• Intake of any whey protein, casein of branched-chain amino acid (BCAA) supplements from 1 month prior to the start of the study
• Blood donation within 3 months prior to the start of the study
• Smoking
• Current participation in another research trial
• Any other argument to believe that the subject is unlikely to successfully complete the full study

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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22 participants in 2 patient groups, including a placebo group

Placebo

Placebo Comparator group

Description:

Only whey protein will be provided

Treatment:

Dietary Supplement: whey protein

Collagen

Experimental group

Description:

A mix of whey protein and collagen peptides will be provided

Treatment:

Dietary Supplement: whey protein + collagen peptide