Effects of Combined Grape Seed Extract and L-citrulline Supplementation on Hemodynamic Responses in Young Males

California Baptist University

Status: Completed

Conditions: Dietary Supplementation

Treatments: Dietary Supplement: Placebo; Dietary Supplement: Grape seed extract

Study type: Interventional

Funder types: Other

Identifiers

NCT05116150

112-1819 EXP

Details and patient eligibility

About

This study was to examine the additive benefits with combined grape seed extract (GSE) and L-citrulline supplementation on hemodynamic responses to dynamic exercise, 11 young, healthy males were recruited for this study.

Full description

The investigators aimed the additive effects of combined grape seed extract (GSE) and L-citrulline supplementation on hemodynamic responses to dynamic exercise, 11 young, healthy males were recruited for this study. Effects of 7 days of combined GSE with L-citrulline supplementation on systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial blood pressure (MAP), cardiac output (CO), total vascular conductance (TVC), and oxygen consumption (O2) were examined at rest and during cycling exercise.

Enrollment: 11 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy males

Exclusion criteria

• cardiovascular and/or pulmonary disease, musculoskeletal disorders, or medications that prevent the safe completion of the exercise protocol

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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11 participants in 2 patient groups, including a placebo group

Randomized double blind grape seed extract design

Active Comparator group

Description:

Grape see extract

Treatment:

Dietary Supplement: Grape seed extract

Dietary Supplement: Placebo

Randomized double blind placebo design

Placebo Comparator group

Description:

Placebo

Treatment:

Dietary Supplement: Grape seed extract

Dietary Supplement: Placebo