Effects of COVID-19 Induced Deconditioning After Long-term High Intensity Resistance Exercise

University of Erlangen-Nürnberg Medical School

Status: Completed

Conditions: Osteoporosis; Sarcopenia

Study type: Observational

Funder types: Other

Identifiers

NCT04444661

FrOST-FU

Details and patient eligibility

About

Osteosarcopenia designates the simultaneous presence of sarcopenia and osteopenia; both chronic conditions of advanced age. Dynamic-resistance exercise (DRT) might be the most powerful agent to fight osteosarcopenia. Indeed, in the present FrOST study, we clearly determine the positive effect of slightly adapted 18 month high-intensity (HIT)-DRT on bone mineral density (BMD), sarcopenia and other health related parameters in osteosarcopenic men. However, after a short training break, COVID-19 induced lock down prevented a re-start of the HIT resistance exercise training in the FrOST cohort.

The aim of the present observational study is thus to determine the effects of 6 months of deconditioning on health related parameters under special regard of osteosarcopenia in this cohort of older men with osteosarcopenia.

Enrollment: 21 patients

Sex: Male

Ages: 74 to 95 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• participants of the FrOST study (NCT03453463)

Exclusion criteria

• medication and diseases with potential impact on study outcomes during the last 26 weeks.

Trial design

21 participants in 2 patient groups

HIT-resistance exercise

Description:

High Intensity Resistance Exercise

Non exercising control

Description:

Control group that maintained life style and physical activity habits