Effects of Cranberry Juice on Risk Factors for Cardiovascular Disease

Mayo Clinic

Status: Completed

Conditions: Atherosclerosis

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT00631306

07-003443

Details and patient eligibility

About

This study is being done to determine if the use of double strength cranberry juice in daily diet will improve endothelial function.

Full description

Study participants will be randomized assigned to drink either placebo (a drink that looks and tastes like cranberry juice, but does not contain cranberry juice) or a double strength Ocean Spray light cranberry juice cocktail for four months.

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects over the age of 18 years old with known or suspected cardiovascular disease including documented CAD by cardiac catheterization, and multiple cardiovascular risk factors will be included, regardless of severity of endothelial dysfunction or previous history of cardiovascular events.
• Subjects with no known history of cardiac disease will also be eligible to participate.
• Subjects must demonstrate endothelial dysfunction via the RH-PAT test (an RH-PAT score of less than 2.0) to continue participating in this study.

Exclusion criteria

• Patients will be excluded if they have confounding factors including, but not limited to, history of renal or liver failure, or relevant food allergies (cranberries, etc.).

Trial design

60 participants in 2 patient groups

Bottle number 615

Description:

Patients are randomized to either Bottle number 615 or Bottle number 429 (actual product vs. placebo). This is a blinded study.

Bottle number 429

Description:

Patients are randomized to either Bottle number 615 or Bottle number 429 (actual product vs. placebo). This is a blinded study.