Effects of Curcumin on Vascular Reactivity (CURCUMIN)

University Hospital, Clermont-Ferrand

Status and phase: Completed; Phase 2; Phase 1

Conditions: Healthy Volunteers (Middle-aged Smokers)

Treatments: Drug: Curcumin

Study type: Interventional

Funder types: Other

Identifiers

NCT01543386

CHU-0113

Details and patient eligibility

About

The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk

Full description

The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk

Enrollment: 21 patients

Sex: All

Ages: 50 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 50 to 70 year-old volunteers
• smokers

Exclusion criteria

• treated hypertension
• treated hypercholesterolemia
• chronic disease
• vegetarian or other unusual diets
• chronic alcoholism

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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21 participants in 1 patient group

curcumin

Other group

Description:

The aim of this study is to determine if an oral loading-dose of curcumin can improve vascular endothelium reactivity in patients with moderate cardiovascular risk

Treatment:

Drug: Curcumin