Effects of Dairy- and Berry-based Snacks on Postprandial Glucose Metabolism in Older People (MAVIRE2)

University of Eastern Finland

Status: Completed

Conditions: Postprandial Hyperglycemia

Treatments: Dietary Supplement: Dairy snack; Dietary Supplement: Berry snack

Study type: Interventional

Funder types: Other

Identifiers

NCT04175353

4249/31/2014 (Other Grant/Funding Number)

MAVIRE2 247124

Details and patient eligibility

About

Malnutrition or its risk is common among older people. To maintain adequate nutrition, increased meal frequency is important. In addition to main meals, regular consumption of nutrient- and energy-dense snacks is recommended. The study examines the post-meal responses to dairy- and berry-based snacks tailored for older people. The plasma concentrations of glucose, insulin and free fatty acids are measured during three hours after snack consumption. In addition, subjective satiety responses and heart rate variability are recorded.

Enrollment: 26 patients

Sex: All

Ages: 65+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Home-dwelling

Exclusion criteria

• Smoking
• Type 1 diabetes
• Type 2 diabetes treated with oral medications or insulin
• Cognitive impairment
• Antibiotic medication within the past 3 months
• Blood donation within the past month

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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26 participants in 5 patient groups

Dairy snack

Experimental group

Description:

Drink high in milk protein, 250 ml

Treatment:

Dietary Supplement: Dairy snack

Orange juice

Active Comparator group

Description:

Regular orange juice, 250 ml

Treatment:

Dietary Supplement: Dairy snack

Berry snack 1

Experimental group

Description:

Bilberry-blackcurrant purée, 139 g

Treatment:

Dietary Supplement: Berry snack

Berry snack 2

Experimental group

Description:

Lingonberry purée, 122 g

Treatment:

Dietary Supplement: Berry snack

Berry soup

Active Comparator group

Description:

Bilberry soup, 250 ml

Treatment:

Dietary Supplement: Berry snack