Effects of Delivery Mode of Cognition Intervention in Early Alzheimer's Disease

Kansas Board of Regents

Status and phase: Completed; Phase 2

Conditions: Alzheimer's Disease

Treatments: Behavioral: Cognitive Training

Study type: Interventional

Funder types: Other

Identifiers

NCT00611312

IIRG-07-57789

11008 (Registry Identifier)

Details and patient eligibility

About

The purpose of this study is to see if an intense two-week long cognitive training program helps the thinking ability of adults with very mild Alzheimer Disease. We anticipate that scores on clinical cognitive tests will be better after the training.

Full description

Twenty of the 30 subjects will be recruited to participate in functional magnetic resonance imaging (fMRI). Scanning will be done while subjects perform a verbal learning task. Ten subjects will be scanned before and after the two week training. Another ten will be scanned twice at a two week interval before beginning the cognitive training.

Enrollment: 25 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of very mild Alzheimer's Disease (CDC of 0.5) and mild Alzheimer's Disease (CDC of 1.0)

Exclusion criteria

• Neurologic disorder other than Alzheimer's disease

Trial design

Primary purpose: Supportive Care

Allocation: Non-Randomized

Interventional model: Single Group Assignment

Masking: None (Open label)

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25 participants in 1 patient group

1

Experimental group

Description:

Cognitive Training

Treatment:

Behavioral: Cognitive Training