Effects Of Detrol LA On Memory And Cognition In Elderly Population

Viatris

Status and phase: Completed; Phase 4

Conditions: Cognition; Memory

Treatments: Drug: Oxybutynin ER; Drug: Tolterodine ER

Study type: Interventional

Funder types: Industry

Identifiers

NCT00411437

A6121154

Details and patient eligibility

About

The primary purpose of the trial is to show that tolterodine ER has no effect on memory and other cognitive abilities in an elderly population

Sex: All

Ages: 65 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male or female subjects with age of 65 - 75 years
• Having a score of greater than or equal to 26 on the Mini-Mental State Exam (MMSE)

Exclusion criteria

• Current or history of bladder outlet obstruction. Previous history of acute urinary retention requiring catheterization, or severe voiding difficulties in the judgment of the investigator, prior to randomization
• Significant hepatic or renal disease, defined as twice the upper limit of the reference ranges regarding serum concentrations of AST, ALT, ALP, urea nitrogen, or creatinine

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind