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Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study

S

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

Status

Not yet enrolling

Conditions

Rhinoplasty Surgery

Treatments

Drug: Remifentanil
Drug: Dexmedetomidine

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology. We planned to compare the patients by recording preoperative and postoperative ECGs. We also planned to record the patients' intraoperative blood pressure, saturation, and pulse rate, rickeragitation scale, and vas score.

Enrollment

72 estimated patients

Sex

All

Ages

17 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • patients with an ASA score of I and between the ages of 17-45 years, who were to undergo general anesthesia with sevofulurane were included in the study.

Exclusion criteria

Patients aged <17 and >45 years, patients with liver and/or kidney failure, obese patients (BMI >30), trauma patients, ASA II-III-IV patients, patients with bleeding disorders, those using drugs that may affect the coagulation system, patients with cardiomyopathy, cerebrovascular disease, immobility, and malnutrition were excluded from the study.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Triple Blind

72 participants in 2 patient groups

Effects of Dexmetomidine
Active Comparator group
Description:
Patients in this group will be given dexmedetomidine infusion during the intraoperative period to provide controlled hypotension.
Treatment:
Drug: Dexmedetomidine
Effects of Remifentanil
Active Comparator group
Description:
Patients in this group will be given remifentanil infusion during the intraoperative period to provide controlled hypotension.
Treatment:
Drug: Remifentanil

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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