Effects of Dietary Nitrate From Vegetable/Fruit Juice on Cerebral Blood Flow Parameters
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About
Nitrate provides the body with an alternative source of Nitric Oxide which plays a large role in promoting blood flow and reducing blood pressure. Nitrate supplementation with vegetable/fruit juice has recently been shown to reduce blood pressure and reduce energy expenditure during low intensity exercise. Such findings combined with the previously known biological effects of nitric oxide would suggest that nitrate supplementation would also impact on blood flow. The aim of this study is to examine the effects of dietary nitrate supplementation via vegetable/fruit juice drink on cerebral (brain) blood flow (using Near Infrared Spectroscopy).
Enrollment
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Volunteers
Inclusion criteria
- healthy young (18-35 years) male and female adults, not vulnerable.
Exclusion criteria
- smoke or consume any tobacco products (even occasionally)
- not proficient in English
- pregnant (or are seeking to become)
- currently taking recreational, over the counter/prescription medication (excluding the contraceptive pill), and/or dietary/herbal supplements.
- any food allergies or sensitivities that are relevant to the study
- history of/current head trauma, learning difficulties, ADHD, dyslexia, migraines or any gastric problems.
Trial design
Primary purpose
Allocation
Interventional model
Masking
40 participants in 2 patient groups, including a placebo group
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Data sourced from clinicaltrials.gov
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