Effects of Dietary Nitrate Intake on Physical Performance of Middle-aged Women

University of Sao Paulo

Status: Enrolling

Conditions: Physical Inactivity; Motor Activity; Postmenopausal; Menorrhagia

Treatments: Other: Beetroot juice NO3 depleted; Dietary Supplement: Beetroot juice rich in nitrate

Study type: Interventional

Funder types: Other

Identifiers

NCT05820321

BEET-MS

Details and patient eligibility

About

Through a randomized, crossover, triple-blind, placebo-controlled clinical trial, 15 physically inactive hypertensive women will participate a 8-day trial, each with two intervention protocols: 1) placebo and 2) beetroot; in which will ingest beet juice with or without NO3 in its composition with a 8-day washout interval.

Enrollment: 15 estimated patients

Sex: Female

Ages: 50 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50 to 65 years old
• Physically inactive
• Postmenopausal diagnosis (amenorrhea for 12 months or more);

Exclusion criteria

• Smoking
• Cardiac failure
• Previous history of acute myocardial infarction and/or stroke;
• Allergy or intolerance to nitrate, gluten, or milk;

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Triple Blind

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15 participants in 2 patient groups, including a placebo group

Experimental (Beetroot juice NO3)

Active Comparator group

Description:

8-day supplementation with beetroot juice rich in NO3 (400mg) during 8 days.

Treatment:

Dietary Supplement: Beetroot juice rich in nitrate

Placebo (Beetroot juice without NO3)

Placebo Comparator group

Description:

8-day supplementation with beetroot juice NO3 depleted during 8 days.

Treatment:

Other: Beetroot juice NO3 depleted