Effects of Dietary Protein Intake From Beef/Pork and Soy/Legumes on Appetite, Mood, and Weight Loss

Purdue University

Status: Completed

Conditions: Weight Loss; Mood; Appetite

Treatments: Other: Beef/Pork; Other: Soy/Legumes

Study type: Interventional

Funder types: Other

Identifiers

NCT01005563

0905008129 (Other Identifier)

Details and patient eligibility

About

The primary aims of this study are to assess the effects of habitual dietary protein intakes across the acceptable macronutrient distribution range with lean beef/pork or soy/legumes as the predominate sources of protein on indices of daily appetite and mood, and on postprandial appetite, mood, energy expenditure, and glycemic responses during energy-restricted weight loss in overweight adults.

Enrollment: 37 patients

Sex: All

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age range: 21 years and older
• Body mass index between 27.0-36.9 kg/m2
• Non-smoking (within the last 6 months)
• Weight stable (< 3 kg (~7 lbs) weight gain or loss within last 3 months)
• Energy need for weight maintenance 1950-2750 kcal/day
• Not dietary restrained
• Menstruating women not pregnant or lactating
• Constant habitual activity patterns (within last 3 months)
• No Acute Illness (or have chronic diseases known to influence protein or energy metabolism)
• Non-diabetic
• Clinically normal blood profiles (within 10% of clinical normalcy)
• Non-hypertensive
• Not taking medications known to influence appetite or metabolism
• Willingness to eat study foods
• Able to travel to testing facility

Exclusion criteria

• Age: <21 years
• Body mass index: outside of the 27.0-36.9 kg/m2 range
• Smoker (currently or within the last 6 months)
• Gained or lost > 3.0 kg (7 lbs) within the last 3 months
• Energy need for weight maintenance < 1950 or > 2750 kcal/day
• Dietary restrained (≥ 14 on Three Factor Eating Questionnaire)
• Pregnant, lactating, or non-menstruating women
• Clinically diagnosed as a diabetic, or with liver or kidney disease/dysfunction, or osteoporosis
• Clinically abnormal blood profiles as identified by our study physician, Arthur Rosen, MD
• Hypertensive
• Taking medications (currently or within the last 3 months) known to influence appetite or metabolism
• Allergies to eggs
• Lactose intolerance
• Unwillingness to eat study foods
• Inability to travel to testing facility

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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37 participants in 2 patient groups

Arm 1: Beef/Pork

Experimental group

Description:

Participants consuming diet with beef/pork as predominate sources of protein

Treatment:

Other: Beef/Pork

Arm 2: Soy/Legumes

Experimental group

Description:

Participants consuming diet with soy/legumes as predominate sources of protein

Treatment:

Other: Soy/Legumes