Effects of Dietary Protein on Undesirable Postprandial Events in Overweight Subjects

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Status: Completed

Conditions: Overweight

Treatments: Dietary Supplement: Postprandial metabolic and functional measures

Study type: Interventional

Funder types: Other

Identifiers

NCT00931151

SURPROL 2

Details and patient eligibility

About

Dietary protein differing by their amino acid composition could modulate undesirable metabolic and functional responses to a meal rich in saturated fat and sugars. This study aims at examining the specific effects of dairy protein with different cysteine contents on the postprandial undesirables effects elicited by the ingestion of a high fat meal in overweight subjects.

Enrollment: 10 estimated patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI between 25 and 30
• Waist circumference > 94 cm

Exclusion criteria

• Allergy to milk protein
• Abusive drug consumption
• Smoking
• Hypertension, diabetes
• High level of physical activity

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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10 participants in 3 patient groups

Casein

Experimental group

Description:

Protein source in the high fat meal is casein

Treatment:

Dietary Supplement: Postprandial metabolic and functional measures

Milk soluble protein

Experimental group

Description:

Protein source in the high fat meal are milk soluble protein

Treatment:

Dietary Supplement: Postprandial metabolic and functional measures

Alpha lactalbumin

Experimental group

Description:

Protein source in the high fat meal is alpha-lactalbumin

Treatment:

Dietary Supplement: Postprandial metabolic and functional measures