Effects of Dietary Proteins on Postprandial Lipaemia and Incretin Responses in Obese Subjects

Aarhus University Hospital

Status: Completed

Conditions: Postprandial Inflammation; Postprandial Lipaemia; Postprandial Incretins

Treatments: Dietary Supplement: Whey Isolate; Dietary Supplement: Whey Hydrolysate; Dietary Supplement: Casein; Dietary Supplement: Alphalact-Albumin

Study type: Interventional

Funder types: Other; Industry

Identifiers

NCT00809874

CERN-PPL-JHJ

Details and patient eligibility

About

The purpose of this study is to determine the effects of dietary protein on blood lipids and gut hormones after a fat-rich meal.

Hypothesis: Certain dietary proteins reduce the amount of fat circulating in the blood stream following a fat rich meal. The effect is dependant of both the quality and the quantity of protein ingested.

Enrollment: 11 patients

Sex: All

Ages: 40 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI >30 kg/m2 & <45 kg/m2

Exclusion criteria

• Diabetes
• lipid lowering drugs
• Liver-, Kidney- and/or Heart Disease
• Serious Hypertension (160/110)

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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11 participants in 4 patient groups

Casein

Active Comparator group

Treatment:

Dietary Supplement: Casein

Whey Isolate

Active Comparator group

Treatment:

Dietary Supplement: Whey Isolate

Whey Hydrolysate

Active Comparator group

Treatment:

Dietary Supplement: Whey Hydrolysate

Alphalact-Albumin

Active Comparator group

Treatment:

Dietary Supplement: Alphalact-Albumin