ClinicalTrials.Veeva

Menu

Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense

U

Universidade do Porto

Status

Completed

Conditions

Healthy

Treatments

Other: Muscle fatigue Protocol

Study type

Interventional

Funder types

Other

Identifiers

NCT06331221
JSA_Fatigue_FADEUP

Details and patient eligibility

About

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

Full description

A randomized controlled crossover trial will be conducted at a biomechanics laboratory with healthy males. All participants will perform with a washout period of 1 week: a control condition (5-minute rest) and 4 local muscle fatigue protocols (concentric of quadriceps; concentric of hamstrings; eccentric of quadriceps; eccentric of hamstrings) in an isokinetic dynamometer at 30º/s. Three maximum voluntary isometric contractions (MVIC) of quadriceps and hamstrings will also be assessed in the beginning of all conditions.

Knee joint position sense will be assessed before and immediately after the fatigue protocols/control condition, through active concentric and eccentric positionings/repositionings, in sitting and prone positions, to a target range of 45º of knee flexion in an isokinetic dynamometer. Surface electromyography electrodes will also be placed on the vastus lateralis and biceps femoris during all procedures.

Enrollment

22 patients

Sex

Male

Ages

18 to 30 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • males aged between 18 and 30 years;
  • without current or previous knee pathology or surgery;
  • with a low or moderate physical activity level, according to the International Physical Activity Questionnaire;
  • normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.

Exclusion criteria

  • those with cardiorespiratory, neurological or vestibular pathologies;
  • with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and
  • those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).

Trial design

Primary purpose

Health Services Research

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

None (Open label)

22 participants in 5 patient groups

Control Condition
No Intervention group
Description:
5-minute rest period.
Quadriceps_Concentric
Active Comparator group
Description:
40 consecutive maximal concentric contractions of quadriceps at 30º/s
Treatment:
Other: Muscle fatigue Protocol
Quadriceps_Eccentric
Active Comparator group
Description:
40 consecutive maximal eccentric contractions of quadriceps at 30°/s
Treatment:
Other: Muscle fatigue Protocol
Hamstrings_Concentric
Active Comparator group
Description:
30 consecutive maximal concentric contractions of hamstrings at 30º/s
Treatment:
Other: Muscle fatigue Protocol
Hamstrings_Eccentric
Active Comparator group
Description:
30 consecutive maximal eccentric contractions of the hamstrings at 30º/s
Treatment:
Other: Muscle fatigue Protocol

Trial contacts and locations

1

Loading...

Central trial contact

Joana Azevedo, MSc

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems