Effects of Different Fresh Gas Flows on Carboxyhemoglobin Levels

Zonguldak Bulent Ecevit University

Status: Completed

Conditions: Fresh Flow; Carboxyhemoglobinemia

Treatments: Device: Radical-7 Pulse CO-Oximeter

Study type: Observational

Funder types: Other

Identifiers

NCT04832256

2015-67-07/07

Details and patient eligibility

About

To observe the effect of different fresh flows (1 L / min and 4 L / min) on the carboxyhemoglobin level non-invasively and continuous measurement and to determine the contribution of smoking to the intraoperative carbon monoxide accumulation.

Enrollment: 64 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA I-II
• Undergo 2-4 hours of elective surgery

Exclusion criteria

• Cardiovascular disease
• diabetes mellitus
• kidney, liver failure
• chronic obstructive pulmonary disease
• patients with opioid sensitivity
• morbidly obese
• personal or family history of malignant hyperthermia
• history of prolonged recovery from anesthesia
• alcohol addicted
• pregnant and breastfeeding women patients allergic to study drugs

Trial design

64 participants in 2 patient groups

High Flow anesthesia

Description:

administered 4 L/min fresh gas flow during general anesthesia

Treatment:

Device: Radical-7 Pulse CO-Oximeter

Low Flow Anesthesia

Description:

administered 1 L/min fresh gas flow during general anesthesia

Treatment:

Device: Radical-7 Pulse CO-Oximeter