Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery

Giresun University

Status: Completed

Conditions: Intraocular Pressure; Disk Herniated Lumbar; Anesthesia

Treatments: Other: Propofol Group; Other: Desflurane Group; Other: Spinal Anesthesia Group

Study type: Interventional

Funder types: Other

Identifiers

NCT06070480

KAEK 04/2020

Details and patient eligibility

About

The aim of this study was to investigate the effects of anaesthesia methods on intraocular pressure during lumbar disc surgery performed in the prone position.

Full description

The study included 75 patients with lumbar disc herniation between the ages of 18-75, with the American Society of Anesthesiologists (ASA) 1-2. The patients were randomly divided into 3 groups: propofol, desflurane, spinal. Intraocular pressure (IOP) was measured at 5 time points throughout surgery, including baseline (T1), 10 minutes after anesthesia (T2), 10 minutes after prone positioning (T3: early prone), 30 minutes after prone positioning (T4: late prone), and 10 minutes after returning to the supine position (T5). Hemodynamic parameters were measured at these time points. Hemoglobin and hematocrit values were measured preoperatively and on the first postoperative day.

Enrollment: 75 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA 1-2 according to the American Society of Anesthesiologists (ASA) Classification.

Exclusion criteria

• Who did not sign the informed consent form,
• patients who required emergency surgery,
• eye surgery recipients,
• subjects with acute or chronic eye diseases other than refractive errors,
• individuals detected to have elevated IOP in preoperative measurements

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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75 participants in 3 patient groups

Spinal Anesthesia Group

Active Comparator group

Description:

Intraocular pressure values of the patients operated with spinal anaesthesia were measured

Treatment:

Other: Spinal Anesthesia Group

Desflurane Group

Active Comparator group

Description:

Intraocular pressure values were measured in patients operated under general anaesthesia with desflurane.

Treatment:

Other: Desflurane Group

Propofol Group

Active Comparator group

Description:

Intraocular pressure values were measured in patients operated under general anaesthesia with desflurane.

Treatment:

Other: Propofol Group