Effects of Different Types of Exercise Interventions in Patients With Type 2 Diabetes

University of Giessen

Status: Unknown

Conditions: Type 2 Diabetes

Treatments: Other: Strength endurance training intervention; Other: Combined aerobic endurance and strength endurance training; Other: Aerobic endurance training intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01377558

Gi-03-2011

Details and patient eligibility

About

The purposes of the study are

• to determine which kind of supervised exercise intervention (aerobic endurance training versus strength endurance training versus combined aerobic endurance and strength endurance training) is more effective in improving the metabolic parameters in typ 2 diabetes patients
• to investigate what kind of intervention is more successful in reduction of concomitant diseases and improving quality of life
• to assess what kind of intervention induces highest effects in long term persistence of these positive changes

Full description

Meta-analyses which evaluated the effects of structured exercise programs in patients with type 2 diabetes demonstrate that regular physical activity improves glycosylated haemoglobin (König et al.: Resistance Exercise and Type 2 Diabetes Mellitus, Deutsche Zeitschrift für Sportmedizin Jahrgang 62, Nr. 1 (2011): 5-9). Sigal et al. proved that either aerobic or resistance training alone improved glycemic control in type 2 diabetes, but the improvements are greatest with combined aerobic and resistance training (Sigal, RJ, et al.: Effects of Aerobic Training, Resistance Training, or Both on Glycemic Control in Type 2 Diabetes, Ann Intern Med. 2007 Sep 18;147(6):357-69).

Therefore, aim of the current study is to compare the effects of aerobic endurance training or resistance endurance training or the combination of aerobic endurance training and resistance endurance training in diabetes type 2 patients without any other lifestyle or dietary interventions.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnoses of type 2 diabetes (ADA criteria)
• admitted diabetes treatments will be diet and oral hypoglycemic agents

Exclusion criteria

• sports intervention >60 minutes per week
• medical conditions
• preproliferative or proliferative retinopathy
• instable coronary heart disease
• inability to perform the scheduled physical activity programs
• acute clinically significant intercurrent diseases

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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100 participants in 4 patient groups

Aerobic endurance training intervention

Experimental group

Description:

Aerobic endurance training

Treatment:

Other: Aerobic endurance training intervention

Strength endurance training intervention

Experimental group

Description:

Strength endurance training

Treatment:

Other: Strength endurance training intervention

Combined training intervention

Experimental group

Description:

Combined aerobic endurance training and strength endurance training intervention

Treatment:

Other: Combined aerobic endurance and strength endurance training

Control group

No Intervention group

Description:

control group