Effects of Different Ventilatory Strategy During Bronchoscopy

Guangzhou Medical University

Status: Not yet enrolling

Conditions: Bronchoscopy

Treatments: Device: Supraglottic jet oxygenation and ventilation; Device: High-flow nasal oxygen; Device: Conventional Oxygen Therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT05956301

20230618

Details and patient eligibility

About

The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic procedures.

Our study aim was to evaluate the efficacy and complications of High-flow nasal oxygen (HFNO) via Supraglottic jet oxygenation and ventilation (SJOV)during flexible bronchoscopy.

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• need for bronchial endoscopy

Exclusion criteria

• life-threatening cardiac aritmia or acute miocardical infarction within 6 weeks need for invasive or non invasive ventilation presence of pneumothorax or pulmonary enphisema or bullae recent (within 1 week) thoracic surgery presence of chest burns presence of tracheostomy pregnancy nasal or nasopharyngeal diseases dementia lack of consent or its withdrawal

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

150 participants in 3 patient groups

Group I

Active Comparator group

Description:

Conventional Oxygen Therapy

Treatment:

Device: Conventional Oxygen Therapy

Group II

Experimental group

Description:

High-flow nasal oxygen

Treatment:

Device: High-flow nasal oxygen

Group III

Experimental group

Description:

Supraglottic jet oxygenation and ventilation

Treatment:

Device: Supraglottic jet oxygenation and ventilation