Effects of Direct Laryngoscopic and Fiberoptic Intubation on Intraocular Pressure

Inonu University

Status: Completed

Conditions: Intraocular Pressure; Intubation Complication

Treatments: Other: Direct laryngoscope; Other: Fiberoptic bronchoscope

Study type: Interventional

Funder types: Other

Identifiers

NCT03003585

Asozkan-2

Details and patient eligibility

About

In this study, the investigators aimed to compare the effects of direct laryngoscopic and fiberoptic endotracheal intubation on intraocular pressure.

Full description

Material and Method: Total of 54 American Society of Anesthesiologist Grade 1-2, Mallampati score 1 or 2, age between 18 to 65 patient planned to undergo nonopthalmic surgery will be included to study. Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, American Society of Anesthesiologist Grade III and IV, body mass index more than 35, difficult intubation, undergo obstetrical surgery and propofol, fentanyl, rocuronium contraindicated will be excluded from the study. Patients will be divided randomly into 2 groups as direct laryngoscopic and fiberoptic intubation group. Patients will be preoxygenated with %100 O2 for 3 minutes then anesthesia will be induced using propofol 2 mg / kg, fentanyl 1 mcg/kg, and rocuronium 0,5 mg / kg in both groups. After 3 minutes mask ventilation, patients will be intubated (women with No:7-7,5, men with No:8-8,5 intubation tube). Systolic blood pressure, diastolic blood pressure, mean arterial pressure, peripheral oxygen saturation,perfusion index will be recorded and intraocular pressure measured by ophthalmologist by tonopen device will be recorded pre-induction (basal), after induction, 1,2,3,5 minutes after intubation, respectively. Period between handling of laryngoscope or fiberoptic device after termination of mask ventilation and obtain end tidal CO2 will be accepted as application time and recorded. Study will be terminated after 5th minute values taken.

Enrollment: 54 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ASA (American Society of Anesthesiologist) Grade 1-2,
• Mallampati score 1 or 2,
• Age between 18 to 65
• Patient planned to undergo nonopthalmic surgery.

Exclusion criteria

• Patients with glaucoma, diabetes mellitus, cardiovascular and pulmonary diseases, ASA Grade III and IV, BMI more than 35,
• Patients with difficult intubation,
• Patients undergoing obstetrical surgery and propofol, fentanyl, rocuronium contraindicated.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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54 participants in 2 patient groups

Fiberoptic bronchoscopy

Active Comparator group

Description:

Evaluate the difference between the two groups about hemodynamic and intraocular pressure responses.

Treatment:

Other: Fiberoptic bronchoscope

Direct laryngoscopy

Active Comparator group

Description:

Evaluate the difference between the two groups about hemodynamic and intraocular pressure responses.

Treatment:

Other: Direct laryngoscope