Effects of DL-endopeptidase Producing Probiotics on Human Intestinal NOD2 Ligands and Related Functions (probiotics)

Zhujiang Hospital

Status and phase: Active, not recruiting; Early Phase 1

Conditions: Microecological Therapy; Probiotic Intervention

Treatments: Other: Oral administration

Study type: Interventional

Funder types: Other

Identifiers

NCT06716047

ZhujiangHZD

Details and patient eligibility

About

We have discovered a type of probiotic that can target activating intestinal NOD2, which is related to a series of human health issues.

Full description

This trial requires the subjects to take probiotics for a certain period of time, and we will collect blood, stool and questionnaires for subsequent testing, efficacy evaluation and safety evaluation.

Enrollment: 30 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Tend to participate the trial
• Willing to provide written informed consent

Exclusion criteria

• Recent use of probiotics, antibiotics, laxatives, or gastrointestinal ulcer medications within the past month.
• Gastrointestinal symptoms (e.g., constipation, abdominal pain, diarrhea, melena, hematochezia) in the past month.
• Other conditions considered by researchers for exclusion

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups, including a placebo group

placebo

Placebo Comparator group

Description:

resistant dextrin

Treatment:

Other: Oral administration

probiotics

Experimental group

Description:

lactobacillus

Treatment:

Other: Oral administration