Effects of E-Cigarette Nicotine Content in Smokers (Nicotine Flux Study)

Virginia Commonwealth University (VCU)

Status: Completed

Conditions: Electronic Cigarette Use

Treatments: Other: Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine; Other: Tobacco product administration and assessment, own brand cigarettes; Other: Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine; Other: Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine; Other: Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04332926

HM20018290

2U54DA036105 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

This study aims to better understand how e-cigarettes (ECIG) nicotine flux impacts several behavioral economic measures of abuse liability.

Enrollment: 44 patients

Sex: All

Ages: 18 to 55 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy (determined by self-report)
• between the ages of 18-55
• willing to provide informed consent
• able to attend the lab and abstain from tobacco/nicotine as required and must agree to use designated products according to study protocol

Exclusion criteria

• Women if they are breast-feeding or test positive for pregnancy (by urinalysis) at screening.
• Some study details about the eligibility criteria are purposely omitted at this time to preserve scientific integrity. Full details will be posted at the conclusion of the study.

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

44 participants in 1 patient group

Experimental

Experimental group

Treatment:

Other: Tobacco product administration and assessment, ECIG 30 Watts, 15 mg/ml nicotine

Other: Tobacco product administration and assessment, ECIG 30 Watts, 8 mg/ml nicotine

Other: Tobacco product administration and assessment, ECIG 30 Watts, 30 mg/ml nicotine

Other: Tobacco product administration and assessment, own brand cigarettes

Other: Tobacco product administration and assessment, ECIG 30 Watts, 0 mg/ml nicotine