Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2

University of Southern California

Status: Completed

Conditions: Cigarette Smoking; Electronic Cigarette Use; Vaping; Cigarette Use, Electronic

Treatments: Other: E-cigarette

Study type: Interventional

Funder types: Other

Identifiers

NCT05958992

Substudy #2: UP-20-00744

Details and patient eligibility

About

This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.

Full description

There are three primary objectives to the study: (1) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect product appeal across young adult e-cigarette users and middle-age/older adult smokers; (2) Determine which dimensions of e-cigarette product diversity differentially affect product appeal in the overall population of tobacco product users as well as affect abuse liability in young adult e-cigarette users and the ability to resist smoking in adult smokers; (3) Determine the affect of product characteristics on e-cigarette nicotine delivery profile.

Enrollment: 461 patients

Sex: All

Ages: 21+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Vapers/E-cigarette Users - Regular use of e-cigarettes/vaping devices containing nicotine

Cigarette Smokers

• Regular use of cigarettes containing nicotine

Exclusion criteria

• Pregnant or planning to become pregnant

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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461 participants in 5 patient groups

E-Liquid 1

Experimental group

Description:

Participants will self-administer an assigned e-liquid.

Treatment:

Other: E-cigarette

E-Liquid 2

Experimental group

Description:

Participants will self-administer an assigned e-liquid.

Treatment:

Other: E-cigarette

E-liquid 3

Experimental group

Description:

Participants will self-administer an assigned e-liquid.

Treatment:

Other: E-cigarette

E-liquid 4

Experimental group

Description:

Participants will self-administer an assigned e-liquid.

Treatment:

Other: E-cigarette

No e-liquid

No Intervention group

Description:

Participants will not receive an e-liquid to self-administer.