Effects of Early and Delayed Time-restricted Eating in Adults With Overweight and Obesity

Federal University of Rio Grande do Sul

Status: Completed

Conditions: Overweight and Obesity; Obesity; Time Restricted Feeding; Intermittent Fasting

Treatments: Behavioral: Dietary Approach

Study type: Interventional

Funder types: Other

Identifiers

NCT04647149

TRE_UFRGS#

Details and patient eligibility

About

Time-restricted eating (TRE) is a dietary approach that aims to increase fasting time and decrease the eating window. Promising TRE effects on weight loss and some cardiometabolic risk factors have been reported. However, there is a lack of randomized clinical trials that directly investigate the effect of TRE at different times of the day (early vs. delayed) in individuals with overweight and obesity. The present study investigates the effects of 8 weeks of TRE performed at different moments of the day on body composition and cardiometabolic parameters in adults with overweight and obesity.

Enrollment: 48 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male and female;
• Body mass index (BMI) between 25 and 34.9 kg/m²;
• Age between 20 and 40 years;
• Not engaged in any structured exercise program;
• Weight stable for ~3 months prior to the beginning of the study;
• Able to give written informed consent.

Exclusion criteria

• Current smoker;
• Cardiometabolic diseases (dyslipidemia, diabetes, hypertension, etc);
• Current treatment with medication or supplements which significantly affect the main studied variables;
• Night-shift workers;
• Night eating syndrome;
• Irregular sleep patterns;
• For women: pregnancy, planned pregnancy (within the study period), lactating or menopause;
• Habitual fasting window >16 hours;
• Concomitant participation in other studies.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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48 participants in 3 patient groups

Early Time-Restricted Eating

Experimental group

Description:

8-hour eating window between 08:00 and 16:00

Treatment:

Behavioral: Dietary Approach

Delayed Time-Restricted Eating

Experimental group

Description:

8-hour eating window between 12:00 and 20:00

Treatment:

Behavioral: Dietary Approach

Control

Experimental group

Description:

12-hour eating window between 08:00 and 20:00

Treatment:

Behavioral: Dietary Approach