Effects of Early Cardiopulmonary Rehabilitation in Patients With Acute Decompensated Heart Failure

Izmir Bakircay University

Status: Enrolling

Conditions: Heart Failure

Treatments: Other: Early Cardiopulmonary Rehabilitation; Other: Routine in-hospital care

Study type: Interventional

Funder types: Other

Identifiers

NCT07155421

bakircaymzeren09

Details and patient eligibility

About

Acute decompensated heart failure (ADHF) is a severe condition characterized by rapid deterioration of cardiac function, leading to impaired oxygen delivery and multi-organ dysfunction. ADHF often results in reduced physical and respiratory capacity, greater dependence on oxygen support, difficulty performing daily activities, and prolonged hospital stays. In recent years, early exercise-based cardiopulmonary rehabilitation (CPR) has been introduced as part of heart failure management. Evidence suggests that early CPR improves overall health and cardiac function in heart failure patients. However, data regarding its effects in ADHF remain limited. While some studies indicate that early CPR enhances physical function, its impact on respiratory parameters and clinical outcomes is less well established.

Cardiopulmonary rehabilitation is a multidisciplinary program designed to promote physical, psychological, and social recovery in patients with cardiovascular and pulmonary diseases. It includes exercise training, education, psychosocial support, and behavioral strategies. Early CPR specifically aims to improve cardiovascular and respiratory functions in heart failure patients. Initiating CPR in the early phase of ADHF may accelerate recovery, strengthen cardiopulmonary function, shorten hospitalization, and improve quality of life.

This study aims to evaluate the effects of early CPR on functional capacity, hemodynamic parameters, and respiratory parameters in patients with ADHF.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients hospitalized with a diagnosis of acute decompensated heart failure
• Being clinically stable

Exclusion criteria

• Having diagnosed pulmonary, neurological, renal, liver, gastrointestinal, orthopedic or oncological pathologies
• Having cardiomyopathy or congestive pericarditis
• Recent heart surgery in the past 6 months
• New or suspected thromboembolic event
• Presence of open wounds, ulcerations or major dermatological diseases in the lower extremities

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

40 participants in 2 patient groups

Early cardiopulmonary rehabilitation group

Experimental group

Description:

Exercise-based cardiopulmonary rehabilitation will be applied to this group during the hospital stay every day for 3 times a day.

Treatment:

Other: Routine in-hospital care

Other: Early Cardiopulmonary Rehabilitation

Control Group

Other group

Description:

Routine in-hospital care will be applied to this group.

Treatment:

Other: Routine in-hospital care