Effects of Energy Drink on Repeated Sprint Performance and Cognitive Function in Athletes

Chien-Wen Hou

Status: Completed

Conditions: Exercise Performance Impairment; Cognitive Function Decline; Fatigue

Treatments: Dietary Supplement: A non-active placebo supplement.; Dietary Supplement: Energy Drink; Dietary Supplement: Caffeine

Study type: Interventional

Funder types: Other

Identifiers

NCT07104188

IRB-2021-021

Details and patient eligibility

About

Energy drinks are often used by athletes before competitions to enhance their performance. Recent research has pointed out that the performance effects of select ingredients have been studied individually but not in combination with caffeine. Therefore, this study is designed to investigate the effects of caffeine, anserine, and elderberry on cognitive function and repeated sprint performance of athletes during a high-intensity exercise protocol.

A double-blind, randomized crossover design will be employed. Three types of supplements will be tested: placebo, caffeine (220 mg), and an energy drink containing 220 mg caffeine, 288 mg anserine, 400 mg elderberry, and 660 mg of a vitamin-mineral mixture. Twelve college athletes will be recruited to complete repeated sprint tests on a cycle ergometer until exhaustion and to undertake a series of cognitive tasks during exercise.

Enrollment: 12 patients

Sex: Male

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy adults aged 18-25
• Currently enrolled college student
• Active members of a collegiate wrestling team (college wrestlers)
• Engaged in regular wrestling training
• Willing and able to provide written informed consent
• Agreed to maintain their usual diet and training frequency during the study period

Exclusion criteria

• Individuals with known caffeine sensitivity
• Any existing health condition that may interfere with high-intensity exercise (e.g., cardiovascular, metabolic, or neurological disorders)
• Inability or unwillingness to follow study instructions

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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12 participants in 3 patient groups, including a placebo group

Placebo Group

Placebo Comparator group

Description:

Participants in this group received a placebo supplement that contained no active ingredients.

Treatment:

Dietary Supplement: A non-active placebo supplement.

Caffeine Group

Active Comparator group

Description:

Participants in this group received a caffeine supplement containing 220 mg of caffeine.

Treatment:

Dietary Supplement: Caffeine

Energy Drink Group

Experimental group

Description:

Participants in this group received an energy drink containing 220 mg of caffeine, 1800 mg of anserine extract, and 400 mg of elderberry extract.

Treatment:

Dietary Supplement: Energy Drink