Effects of Energy Drinks on Sleep and Cardiovascular Health

Mayo Clinic

Status: Completed

Conditions: Caffeine; Healthy

Treatments: Other: Placebo Drink; Other: Energy Drink

Study type: Interventional

Funder types: Other

Identifiers

NCT05503732

21-012902

Details and patient eligibility

About

The purpose of this study is to learn about the change in quality of sleep, structural organization of sleep, and cardiovascular responses after consuming an energy drink compared to a placebo drink with no caffeine or stimulants.

Enrollment: 54 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults 18 years of age and older.
• Healthy subjects without known cardiovascular disease and thyroid disease.
• Subjects who are on no medications (except oral contraceptive pill).
• Nonsmokers.
• No prior history of caffeine sensitivity or allergy.

Exclusion criteria

• Subjects with known cardiovascular or thyroid disease.
• Subjects currently taking medications other than oral contraceptive pill.
• Smokers.
• Prior history of caffeine sensitivity or allergy.
• Pregnancy.
• Subjects who regularly consume energy drinks.
• Subjects who typically go to sleep after midnight.
• Subjects who traveled across 2 time zones in the last 7 days.
• Shift workers.
• Subjects who have or are suspected to have sleep apnea.
• Subjects who have a body mass index > 35kg/m^2.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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54 participants in 2 patient groups

Energy drink first, then placebo drink

Experimental group

Description:

Subjects will consume two 16-oz energy drinks before sleep for the first study visit, then consume two 16-oz identical looking placebo drink before sleep at the second study visit.

Treatment:

Other: Energy Drink

Other: Placebo Drink

Placebo drink first, than energy drink

Experimental group

Description:

Subjects will consume two 16-oz identical looking placebo drink before sleep at the fist study visit, then consume two 16-oz energy drinks before sleep for the second study visit.

Treatment:

Other: Energy Drink

Other: Placebo Drink