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Effects of Exercise and Cognitive Training on Cognitive Function in Older Adults

NeuroTherapia, Inc. logo

NeuroTherapia, Inc.

Status

Completed

Conditions

Aging
Alzheimer's Disease

Treatments

Other: Exercise Training
Other: Cognitive Training
Other: Educational Sessions
Other: Flexibility Training

Study type

Interventional

Funder types

Other
NIH

Identifiers

NCT01038726
NIH AG035775-01

Details and patient eligibility

About

The purpose of this study is to gain a better understanding of the effects of exercise and cognitive training on improving brain function in healthy older adults who may be at risk for developing Alzheimer's Disease.

Enrollment

108 patients

Sex

All

Ages

60 to 85 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • First or Second-degree relative of someone with Alzheimer's Disease
  • Not currently engaging in regular exercise
  • Able to undergo an MRI
  • Fluent in English

Exclusion criteria

  • Neurological illnesses/conditions
  • Medical illness/conditions that may affect brain function
  • Any unstable or severe cardiovascular disease or asthmatic condition
  • Severe depressive symptoms
  • Inability to walk unassisted

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

108 participants in 4 patient groups

Exercise Training
Active Comparator group
Treatment:
Other: Exercise Training
Combined Cognitive/Exercise Training
Active Comparator group
Treatment:
Other: Exercise Training
Other: Cognitive Training
Cognitive Training
Active Comparator group
Treatment:
Other: Cognitive Training
Combined Low Intensity Training
Active Comparator group
Treatment:
Other: Educational Sessions
Other: Flexibility Training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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