Effects of Exercise Behavior Modification on Plasma Adiponectin and Insulin Resistance in High Risk Subjects of Diabetes

National Taiwan University

Status: Completed

Conditions: Diabetes Mellitus

Treatments: Behavioral: General instruction and education; Behavioral: Physical activity promoting intervention

Study type: Interventional

Funder types: Other

Identifiers

NCT01136096

DOH94-HP-1105 (Other Grant/Funding Number)

9261701067

DOH93-HP-1105 (Other Grant/Funding Number)

Details and patient eligibility

About

Investigators hypothesized home-based exercise intervention was beneficial to those who have had diabetic risk factor for type 2 diabetes mellitus

Full description

This randomized clinical trial was designed to investigate whether a home-based exercise could improve adiponectin levels, exercise behavior and metabolic risk factors (insulin resistance, metabolic components and physical fitness) in subjects with at least a diabetic risk factor for type 2 diabetes mellitus. Participants were randomly allocated to either a control group or a home-based exercise group. All participants were evaluated for outcome measures at baseline, and at 3-month 6-month and 9-month follow-up after engaging in the intervention.

Enrollment: 216 patients

Sex: All

Ages: 20 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• At least one of the following criteria as following: BMI >=24 kg/m*m, hypertension, dyslipidemia, fist-degree relatives of parents with type 2 diabetes, impaired glucose tolerance, gestational diabetes and delivering a babt weighing >=4.0 kg
• Ability of understanding Chinese or Taiwanese

Exclusion criteria

• Diabetes
• Receiving treatment with insulin or oral hypoglycemic agents
• Any other serious illness that prohibit them to undertake fitness evaluation

Trial design

216 participants in 2 patient groups

Lifestyle counseling

Experimental group

Description:

To promote participants' exercise behaviors with individualized home-based exercise program was designed based on the Health Belief Model and Transtheoretical Model

Treatment:

Behavioral: Physical activity promoting intervention

Control

Other group

Description:

Received oral instruction and written general education information without individualized exercise program

Treatment:

Behavioral: General instruction and education