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Effects of Exercise Modality on Abdominal Obesity and Health Risk Factors in Older Men and Women

Q

Queen's University

Status

Completed

Conditions

Abdominal Obesity

Treatments

Other: Aerobic Exercise (AE)
Other: Resistance Exercise (RE)
Other: Resistance and Aerobic Exercise (RAE)

Study type

Interventional

Funder types

Other

Identifiers

NCT00520858
Ross2002

Details and patient eligibility

About

The prevalence of abdominal obesity in the elderly is increasing at alarming rates and thus, requires immediate attention. By comparison to younger adults, obesity reduction in the elderly presents a unique challenge and requires an innovative approach. We propose a novel approach to investigate the effects of different exercise types as independent treatment strategies for the reduction of obesity and related health risk factors in older men and women. We propose that exercise without caloric restriction will be associated with modest weight loss (3-5%), that in turn will be associated with significant reduction in abdominal obesity, insulin resistance, and a corresponding increase in skeletal muscle mass and function. We will determine the separate effects of resistance and aerobic exercise on these primary outcome variables, and, whether a treatment strategy that combines the two is optimal.

Enrollment

145 patients

Sex

All

Ages

65 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Men and women between 65 and 80 years of age.
  • Men and women are self-sufficient, sedentary, abdominally obese (BMI between 27 and 34.9 kg/m2; waist circumference greater than 88 cm in women and 102 cm in men), weight stable (± 2 kg) for 6 months prior to the beginning of the study, be non-smokers, and not diabetic.
  • We will study elderly women who are not taking hormone replacement therapy to create a homogeneous population in whom the effect of exercise on the principal outcome variables can be evaluated with minimal confounding.

Exclusion criteria

  • Smokers and diabetics.
  • Women taking hormone replacement therapy.

Trial design

145 participants in 4 patient groups

C
No Intervention group
RE
Active Comparator group
Description:
Resistance Exercise
Treatment:
Other: Resistance Exercise (RE)
AE
Active Comparator group
Description:
Aerobic Exercise
Treatment:
Other: Aerobic Exercise (AE)
RAE
Active Comparator group
Description:
Resistance and Aerobic
Treatment:
Other: Resistance and Aerobic Exercise (RAE)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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