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Effects of Exercise on Obstructive Sleep Apnea Severity in Elderly

F

Federal University of Paraíba

Status

Unknown

Conditions

Sleep-disordered Breathing
Sleep Disorder; Breathing-Related
Obstructive Sleep Apnea

Treatments

Other: Aquatic exercise training program

Study type

Interventional

Funder types

Other

Identifiers

NCT04120428
05768912401

Details and patient eligibility

About

Obstructive sleep apnea syndrome (OSAS) is defined as a total cessation of upper airway flow for at least 10 seconds. OSAS is considered under diagnosed and it is assessed by a full-night sleep polysomnography. Continuous positive airway pressure (CPAP) is considered the first line treatment to OSAS, however physical exercise has emerged as an adjunct and/or alternative strategy to CPAP in OSAS patients.

Full description

Obstructive sleep apnea syndrome (OSAS), which comprises repeated episodes of total cessation of upper airway flow during sleep, is an underdiagnosed diasease and is closely related to major physiological desadjustments that compromises the systemic health of the human organism, including triggering death events; It is not surprising, therefore, that the prevalence of OSAS in adults and elderly varies widely.

Continuous positive airway pressure (CPAP) is the instrument used as first-line treatment for OSAS because it has significant responses in attenuating the severity of the syndrome, however, the design and logistical operation of the use of this instrument compromise the adherence to OSAS treatment .

In this sense, strategies such as regular exercise practice have promising initial results for the treatment of OSAS, despite the gaps that still exist due to the scarcity of studies completed in this area. To this end, it should be noted that studies evaluating the effects of exercise on the severity of OSAS deal mostly with adults / middle-aged adults in aerobic and / or resistance exercise practices performed in a terrestrial environment with alternation only of the ergometer used. Studies on physical exercise and OSAS in the elderly present marked scarcity and only one randomized clinical trial administered to elderly men was found.

The prescription of physical exercise for the elderly requires some precautions and precautions arising from the maladjustments that senescence promotes and that compromise the functionality of organic systems. These misfits include, among other things, the attenuation of lean mass with consequent reduction in muscle strength and dynamic balance; Such damages trigger, in the elderly, fall events that, linked to the reduction of bone mineral density due to aging, not infrequently lead to the physical and functional disability of the elderly.

Physical exercise performed in the aquatic environment, therefore, emerges as a safe and effective alternative in promoting physical and functional improvements for various populations due to the physical principles of water that promote buoyancy, reduction of joint stress, subjective perception of pain and exercise fatigue.

Therefore, the aim of the present study is to evaluate the effects of a 24-week aquatic training program on the severity of obstructive sleep apnea syndrome in older women and is justified in the emerging needs of 1) finding alternative solutions to CPAP use. , 2) use the practice of physical exercise as a tool in mitigating OSAS risk factors and severity; and 3) promote strategies of physical exertion as safe as they are effective for the elderly population to combat OSAS.

Enrollment

32 estimated patients

Sex

Female

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Elderly women (60 years old or aged)
  • Apparently healthy
  • High risk to develop OSAS
  • Diagnosed with moderate to severe OSAS
  • No treated to OSAS with CPAP
  • No use of any hypnotic medicine before or during the study

Exclusion criteria

  • Cardiovascular, pulmonary or metabolic uncontrolled diseases
  • Inability to perform the experimental protocol or keep the usual daily life
  • Morbid obesity by body mass index

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

32 participants in 2 patient groups

Experimental protocol
Experimental group
Description:
24-week aquatic exercise training program
Treatment:
Other: Aquatic exercise training program
Control protocol
No Intervention group
Description:
Maintain lifestyle routine as usual

Trial contacts and locations

1

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Central trial contact

Bruno T Barbosa, PhD Student

Data sourced from clinicaltrials.gov

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